Journal of Exotic Pet Medicine
Volume 16, Issue 1 , Pages 45-48 , January 2007

Taenia taeniaeformis-induced Metastatic Hepatic Sarcoma in a Pet Rat (Rattus norvegicus)

  • Armando R. Irizarry-Rovira, DVM, PhD

      Affiliations

    • Department of Pathology, Eli Lilly and Company, Greenfield, IN 46140 USA
    • Corresponding Author InformationAddress correspondence to: Dr. Armando R. Irizarry-Rovira, PO Box 708, Greenfield, IN 46140.
    • ,
  • Alexander Wolf, DVM

      Affiliations

    • Avian and Exotic Animal Clinic of Lafayette, Lafayette, IN 47904 USA
    • ,
  • Matthew Bolek, PhD

      Affiliations

    • School of Biological Sciences, University of Nebraska, Lincoln, NE 68588-0118 USA.

References 

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  2. Hanes MA. Fibrosarcomas in two rats arising from hepatic cysts of Cysticercus fasciolaris. Vet Pathol. 1995;32:441–444
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  5. Woolley PG, Wherry WB. Notes on twenty-two spontaneous tumors in wild rats (R. norvegicus). J Med Res. 1911;25:205–216
  6. McCoy GW. A preliminary report on tumors found in wild rats. J Med Res. 1909;31:285–296
  7. Jaquet J, Lemarinier M. Recherches sur un sarcome du rat induit primitivement pasr la alrve d’un tenia du chat. Bull Acad Vet Fr. 1975;48:325–338
  8. Gardiner CH, Poynton SL. In: An Atlas of Metazoan Parasites in Tissues (Morphological characteristics of cestodes in tissue sections). Washington DC: Armed Forces Institute of Pathology; 1999;p. 50–55
  9. Bullock FD, Curtis MR. A study of the reactions of tissues of the rat’s liver to the larvae of Taenia crassicollis and the histogenesis of Cysticercus sarcoma. J Cancer Res. 1924;8:446–481
  10. Dunning WF, Curtis MR. Attempts to isolate the active agents in Cysticercus fasciolaris. Cancer Res. 1953;13:838–842
  11. Bullock FD, Curtis MR. Types of cysticercus tumors. J Cancer Res. 1925;9:425–443
  12. Al-Sadi HI, Youkana SO, Dauod MS. Fibrosarcoma in association with Cysticercus fasciolaris (Taenia taeniaeformis) infection in laboratory mice. Iraqi J Vet Sciences. 2000;93:289–296
  13. Burger CJ, Rikihisa Y, Lin YC. Taenia taeniaeformis: inhibition of mitogen induced proliferation and interleukin-2 production by rat splenocytes by larval in vitro product. Exp Parasitol. 1986;62:216–222
  14. Mathur CS, Johnson S. Serum cholesterol in the house rat (Rattus rattus) naturally infected with some helminth parasites. Helminthologia. 1986;23:231–236
  15. Cook RW, Trapp AL, Williams JF. Pathology of Taenia taeniaeformis infection in the rat: hepatic, lymph node, and thymic changes. J Comp Pathol. 1981;91:219–226
  16. Ansari A, Williams JF. The eosinophilic response of the rat to infection with Taenia taeniaeformis. J Parasitol. 1976;62:728–736
  17. Konno K, Abella JA, Oku Y, et al. Histopathology and physiopathology of gastric mucous hyperplasia in rats heavily infected with Taenia taeniaeformis. J Vet Med Sci. 1999;61:317–324
  18. Oku Y, Yamanouchi T, Matsuda K, et al. Retarded gastric acid secretion in rats infected with larval Taenia taeniaeformis. Parasitol Res. 2002;88:872–873
  19. Konno K, Oku Y, Nonaka N, et al. Hyperplasia of gastric mucosa in donor rats orally infected with Taenia taeniaeformis eggs and in recipient rats surgically implanted with the larvae in the abdominal cavity. Parasitol Res. 1999;85:431–436
  20. Lagapa JT, Oku Y, Nonaka N, et al. Taenia taeniaeformis larval product induces gastric mucosal hyperplasia in SCID mice. Jpn J Vet Res. 2002;49:273–285
  21. Lin YC, Rikihisa Y, Kono H, et al. Effects of larval tapeworm (Taenia taeniaeformis) infection on reproductive functions in male and female host rats. Exp Parasitol. 1990;70:344–352
  22. Ito A, Sakakibara Y, Ma L, et al. Ultrasonographic and serologic studies of experimental cysticercosis in rats infected with Taenia taeniaeformis. Parasite Immunol. 1998;20:105–110
  23. Perry RL, Williams JF, Carrig CB, et al. Radiologic evaluation of the liver and gastrointestinal tract in rats infected with Taenia taeniaeformis. Am J Vet Res. 1994;55:1120–1126
  24. Eom KS, Kim SH, Rim HJ. Efficacy of praziquantel (Cesocide injection) in treatment of cestode infections in domestic and laboratory animals. Korean J Parasitol. 1988;26:121–126
  25. Thomas H, Andrews P, Mehlhorn H. New results on the effect of praziquantel in experimental cysticercosis. Am J Trop Med Hyg. 1982;31:803–810
  26. Ito A, Hashimoto A. Vaccination with hatched but non-activated, non-viable oncospheres of Taenia taeniaeformis in rats. J Helminthol. 1993;67:165–168
  27. Ito A, Bogh HO, Lightowlers MW, et al. Vaccination against Taenia taeniaeformis infection in rats using a recombinant protein and preliminary analysis of the induced antibody response. Mol Biochem Parasitol. 1991;44:43–49

PII: S1557-5063(06)00181-9

doi: 10.1053/j.jepm.2006.11.008

Journal of Exotic Pet Medicine
Volume 16, Issue 1 , Pages 45-48 , January 2007

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